Generally, a lacuna is a gap. The term may refer to:
- Lacuna (manuscripts), a missing section of text
- Lacuna (music), an extended silence in a piece of music
- Lacuna (linguistics), a lexical gap in a language
- Lacuna (law) is the lack of law or of a legal source addressing a situation
- Lacuna (histology), a small space containing an osteocyte in bone or chondrocyte in cartilage
- Lacuna model, a tool for unlocking culture differences or missing "gaps" in text
- Lacunar amnesia, in psychology, amnesia about a specific event
- Lacuna (geology), a large gap in the stratigraphic record, sometimes called a hiatus or unconformity
- Petrovsky lacuna, a region where the fundamental solution of a differential equation vanishes.
Lacuna may also refer to:
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