Locke may refer to:

People

• Locke (surname), information about the surname and list of people
• John Locke (1632–1704), English philosopher

Fictional characters

• John Locke (Lost), a character in the television series Lost
• Locke Cole, a character in the video game Final Fantasy VI
• Locke Lamora, the protagonist of Scott Lynch (author)'s Gentlemen Bastard Sequence.
• Locke the Echidna, a character in the Sonic the Hedgehog comic books
• Locke, a main character of the manga Locke the Superman
• Locke, a pseudonym of Peter Wiggin, a character in the novels by Orson Scott Card

Places

In the United States:

• Locke, California, a town in Sacramento County
• Locke, Indiana
• Locke Township, Michigan, a township located in Ingham County
• Locke, New York, a town in Cayuga County
• Mount Locke, in the Davis Mountains of West Texas
• Locke High School, Los Angeles, California

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