Macedonian Empire can refer to:

• the era of expansion of Macedonia under Philip II of Macedon and Alexander the Great, 359-323 BC
  • the Empire established by Alexander the Great in 333-323 BC, see Conquests of Alexander the Great
  • the successor empires of the Diadochi
    • Ptolemaic Empire
    • Seleucid Empire
• First Bulgarian Empire (Macedonian Empire is sometimes used to refer to the empire of Samuil of Bulgaria in the historiography of former Yugoslavia and its successor countries)

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