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Megalopolis (Greek for large city, great city) may refer to:

• Megalopolis (city type), an extensive metropolitan area or a long chain of continuous metropolitan areas.
  • Jean Gottmann coined this term and later used it as the title of his 1961 book about the northeastern seaboard of the United States.
  • See also, Megacity, Agglomeration, or Ecumenopolis
• Megalopolis, Greece, now known as Megalópoli
• Aphrodisias, a small city in Caria, Asia Minor, previously named Megale Polis
• Doomed Megalopolis, an anime rendition of the Japanese literary epic Teito Monogatari

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